Science-Based Medicine

One reason mouse studies often don’t translate to humans very well (Mo, 26 Aug 2019)
Mouse models are often used as preclinical models of human disease, but the number of drugs that succeed in mice but go on to be approved as a drug for humans is only about one in ten. A new study comparing gene expression in the cells of human brains with those of mouse brains sheds new insight into why.
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Science-Based Satire: Children of Anti-Vaccine Parents More Likely to Refuse Cootie Shot (Fri, 23 Aug 2019)
Are the children of anti-vaccine parents refusing their cootie shots? Are we at risk of seeing outbreaks in our schools? They do say that the organic, non-GMO apples don't fall far from the tree. No, this is satire. Everyone knows that the cootie virus can only be found in government research laboratories.
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The floor is yours (Thu, 22 Aug 2019)
What topics would you like to see covered at Science-Based Medicine? Open thread today for your suggestions and comments.
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Maternal Fluoride and IQ (Wed, 21 Aug 2019)
New study purporting to show correlation between fluoride and IQ comes under heavy criticism.
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Ebola: Science Is Making Progress (Tue, 20 Aug 2019)
Good news! Research on Ebola has identified a 100% effective vaccine and medications that produce a 90% survival rate.
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The Vaccine Guide: Cherry picked studies and deceptive highlighting in the service of antivaccine pseudoscience (Mon, 19 Aug 2019)
The Vaccine Guide is a website and a book by Ashley Everly, a "toxicology consultant" for Health Freedom Idaho. It's been making the rounds in the antivaccine underbelly of social media lately and basically consists of screenshots of cherry picked studies, articles, and web pages, with Everly's highlighting passages to provide an antivaccine spin. It's clever in a way, but also rather lazy. Don't fall for it.
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The DC wants to play PCP on your dime: H.R. 3654 forces Medicare to cover full chiropractic scope of practice (Thu, 15 Aug 2019)
A bill pending before Congress (H.R. 3654) would expand Medicare coverage of chiropractic services to their full scope of practice under state laws. Chiropractors claim they are primary care physicians and want to force Medicare to pay them as such, just like an M.D. or D.O.
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FDA Warns About Miracle Mineral Solution (Wed, 14 Aug 2019)
Jim Humble is still selling his industrial bleach as a fake cure, and the FDA gives another toothless warning.
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Vitamin D and Diabetes: Another Case Where Supplementation Sounded Like a Good Idea But Wasn’t (Tue, 13 Aug 2019)
A new study shows vitamin D supplements don't prevent diabetes. But there are still unanswered questions.
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Americans still (mostly) trust scientists and doctors, but there are some troubling warning signs (Mon, 12 Aug 2019)
Given all the denial of the science behind vaccines, GMOs, evolution, and climate science, you might think that Americans in general distrust scientists and physicians. It's actually not true. Trust in scientists and doctors remains high, but there are still areas where mistrust of scientists is a significant problem. What can be done?
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Put it Over There with the Others: More “Promising Preliminary” Evidence for Acupressure (Fri, 09 Aug 2019)
Another day, another legitimate journal publishing a preliminary study practically designed to spit out a positive result. Also, acupuncture robots?
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Activated charcoal, the wellness scam (Thu, 08 Aug 2019)
Charcoal lemonade is yet another detox scam aimed at separating customers from their money.
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Gary Null’s Attack on SBM (Wed, 07 Aug 2019)
Gary Null's fact- and logic-free attack on SBM.
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What Does It Feel Like to Die? (Tue, 06 Aug 2019)
We're all going to die; we wonder what it will feel like. This book describes what typically happens during the period between diagnosis of a fatal illness and death.
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Is today’s generation of children “the sickest generation”? (Mon, 05 Aug 2019)
Presidential candidate and New Age self-help guru Marianne Williamson has been repeating a claim that over half of our children have chronic illness and implying that the expansion of the vaccine schedule since the late 1980s is responsible. But is it true? Are over half of our children sick? Is this "the sickest generation"?
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Anti-vaccination ideology in chiropractic continuing education and conference (again!) (Thu, 01 Aug 2019)
Yet another chiropractic pediatrics conference features anti-vaccination ideology. Chiropractic institutions approve anti-vaccination CE course content. To protect public health, if chiropractic regulators won't stop this, the states should do it for them.
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Study on Acupuncture for Angina (Wed, 31 Jul 2019)
Another acupuncture study claims positive results, but is plagued by methodological flaws and dubious results.
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American Family Physician Endorses Acupuncture (Tue, 30 Jul 2019)
A CME article in American Family Physician misrepresents the evidence, claiming acupuncture has been proven safe and effective. An accompanying editorial gives despicable advice on how to manipulate patients to accept this theatrical placebo.
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For-profit stem cell clinics, universities, and “pay-to-play” clinical trials for autism (Mon, 29 Jul 2019)
Stem cell therapies show great promise, but as yet the vast majority of that promise has not been validated in rigorous clinical trials. Unfortunately, for-profit stem cell clinics are running clinical trials that require patients to pay to be part of it. These trials are not rigorous. Even more unfortunately, it appears that some universities are also running "pay-to-play" clinical trials that bear an uncomfortable resemblance to those run by for-profit clinics.
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Think Twice Before Giving Young Children Reflux Medications (Fri, 26 Jul 2019)
A recent study demonstrates an association between reflux medications in infancy and increased risk of fractures in early childhood, yet another reason to be cautious when using pharmaceutical interventions to manage a mostly benign and self-limited condition.
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Zapping Antipsychiatry ECT Nonsense (Thu, 25 Jul 2019)
These days people's perceptions of electroconvulsive therapy have a fictionalized understanding of what it is, and its harms. The reality is quite different.
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Shaping Opinions About Science and Medicine (Wed, 24 Jul 2019)
Responding to a commentary with all the usual anti-science tropes.
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Vyleesi: New Drug for Hypoactive Sexual Desire in Women (Tue, 23 Jul 2019)
New drug to treat hypoactive sexual desire in women, Vyleesi, is not very effective and has several drawbacks. It is NOT Viagra for women.
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A new study reinforces the conclusion that autism is primarily genetic (Mon, 22 Jul 2019)
Last week, the largest epidemiological study of its kind was published and concluded, once again, that autism is primarily due to genes and that the environmental component of autism risk is much smaller. Not surprisingly, once again antivaxers didn't want to hear that message.
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Medicare proposal covers acupuncture for back pain study participants: A prelude to full coverage? (Thu, 18 Jul 2019)
Medicare coverage of acupuncture is under consideration. A new proposal would provide coverage to Medicare patients participating in studies of acupuncture for back pain. This research would be used in making a final decision.
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The Latest Ebola Outbreak (Wed, 17 Jul 2019)
The second largest Ebola outbreak is underway. This time we have an effective vaccine, but political unrest and distrust of science may be our real vulnerability.
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Bee Stings for Arthritis (Tue, 16 Jul 2019)
Bee sting therapy may be somewhat effective for arthritis, but it can't be recommended.
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Bad Documentary Review: Family Shots (Mon, 15 Jul 2019)
Amazon removed a number of anti-vax documentaries in March but a few still remain unfortunately. Family Shots is a anti-vax propaganda film pretending to be a documentary about a father trying to find out if vaccines are safe. It also got government funding to be made. Yeah...
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A Canadian Journalist Calls Out Pediatric Chiropractic Again, and the Canadian Chiropractic Association Responds…Again (Fri, 12 Jul 2019)
The National Post has published another quality article pointing out the absurdity of infant chiropractic care. The Canadian Chiropractic Association's attempt at a rebuttal falls flat.
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CBD Oil: The new miracle cure (Thu, 11 Jul 2019)
CBD oil is hyped as a miracle product to treat virtually everything. What is the evidence to support this?
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